Hundreds of thousands that people worldwide suffering about hypertension, becoming an important risk factor for kidney problems, stroke, and cardiovascular disease. In order to prevent such problems along with improving patient outcomes, blood pressure can only be properly managed. The purpose of this review is to provide an extensive examination of the state of antihypertensive treatments and approaches, including prescription drugs, adjustments to lifestyles, and device-based treatments.To find significant studies and recommendations on the medical management of hypertension, an extensive review of the main databases was carried conducted. The biological makeup of hypertension, risk identification, and treatment modalities—including combo and monotherapy—are all discussed in the review