International Research and Academic scholar society

IRASS Journal of Applied Medical and Pharmaceutical Sciences

Issue-5(May), Volume-3 2026

1. Microbial Spectrum and Antimicrobial Resistance in Burn Wound Infectio...
1

Hoque MM*, Uddin MN & Kausar S...
MBBS, MCPS, DCP, FCPS (Microbiology), Adviser Specialist in Pathology, AFIP, Dhaka Cantonment
1-6
https://doi.org/10.5281/zenodo.20130181

Background: Burn wound infections are a major cause of morbidity and mortality, particularly following mass casualty events where healthcare systems are rapidly overwhelmed. On 21 July 2025, an aviation disaster in Dhaka, Bangladesh resulted in a sudden influx of patients with severe burn injuries, creating significant challenges for infection control and antimicrobial management. Objective: This study aimed to characterize the microbiological profile and antimicrobial resistance patterns of burn wound infections among victims of a mass casualty aviation disaster in Bangladesh. Methods: This observational, cross-sectional study was conducted at the National Institute of Burn and Plastic Surgery and the Combined Military Hospital (CMH), Dhaka, from 22 July to 22 August 2025. A total of 40 burn wound samples from hospitalized patients with clinically suspected infections were analyzed. Microbial isolation and identification were performed using standard culture techniques. Antimicrobial susceptibility testing was carried out using the Kirby–Bauer disk diffusion method and the VITEK® 2 automated system, with interpretation according to CLSI M100 guidelines (2024). Results: A total of 46 microbial isolates were recovered. Gram-negative bacteria predominated (78.3%), followed by Gram-positive bacteria (17.4%) and fungi (4.3%). Pseudomonas spp. were the most common pathogens (47.8%), followed by Staphylococcus aureus (17.4%), Klebsiella spp. (13.0%), and Acinetobacter spp. (8.7%). High resistance to fluoroquinolones and carbapenems was observed among Gram-negative isolates. Pseudomonas spp. showed preserved susceptibility to piperacillin–tazobactam (81.8%) and colistin (100%). Fifty percent of S. aureus isolates were methicillin-resistant, while all remained susceptible to vancomycin and linezolid. Conclusion: Burn wound infections following this mass casualty aviation disaster were predominantly caused by multidrug-resistant Gram-negative bacteria, particularly Pseudomonas spp. The findings underscore the need for early microbiological surveillance, rational antimicrobial use, and strengthened infection prevention strategies to improve outcomes in disaster-related burn care.

2. Assessment of Breast Cancer Knowledge and Screening Services amongst W...
1

Musa Yakubu*, Ojowu Margaret Y...
Department of Community Medicine, Federal Medical Centre Gusau Zamfara State Gusau, Nigeria
7-13
https://doi.org/10.5281/zenodo.20181917

Breast cancer is a global public health burden, with persistently low awareness and limited practice of preventive examinations. Mortality has risen sharply, making it the fifth leading cause of death and the most common cancer among women worldwide. While early detection through self-examination, clinical evaluation, and mammography improves prognosis, most patients in sub-Saharan Africa, particularly Nigeria, present at late stages due to poor awareness, lack of organized screening programs, and inadequate diagnostic and treatment facilities. A cross-sectional descriptive study amongst 303 women of reproductive age group was used to assess the awareness, knowledge and screening practices of breast cancer among living in military cantonments in Kaduna State, Nigeria. The results show a progressive level of low awareness of breast self-examination, clinical selfexamination and mammography, underscoring the urgent need for intensified awareness campaigns and empowerment initiatives to encourage women to take responsibility for their health and wellbeing.